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Recombinant Human Forkhead box protein P3 (FOXP3) - 100 ug

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    Garanzia di rimborso di 30 giorni
    Spedizione: 2-3 giorni lavorativi

    The FOXP3 gene is a critical transcription factor on the X chromosome that acts as the "master regulator" for the development and function of regulatory T cells (Tregs). It drives immune tolerance, preventing autoimmunity by suppressing excessive immune responses. Mutations in FOXP3 cause IPEX syndrome (immune dysregulation, polyendocrinopathy, enteropathy, X-linked), a severe autoimmune condition.

    Purity: Greater than 85% as determined by SDS-PAGE.
    Target Names: FOXP3
    Uniprot No.: Q9BZS1
    Alternative Name: Scurfin
    Species: Homo sapiens (Human)
    Expression system: E.coli
    Expression Region: 1-417aa
    Mol. Weight: 53.2 kDa
    Protein Length: Full Length of Mature Protein
    Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged

    Target Protein Sequence:
    MPNPRPGKPSAPSLALGPSPGASPSWRAAPKASDLLGARGPGGTFQGRDLRGGAHASSSSLNPMPPSQLQLPTLPLVMVAPSGARLGPLPHLQALLQDRPHFMHQLSTVDAHARTPVLQVHPLESPAMISLTPPTTATGVFSLKARPGLPPGINVASLEWVSREPALLCTFPNPSAPRKDSTLSAVPQSSYPLLANGVCKWPGCEKVFEEPEDFLKHCQADHLLDEKGRAQCLLQREMVQSLEQQLVLEKEKLSAMQAHLAGKMALTKASSVASSDKGSCCIVAAGSQGPVVPAWSGPREAPDSLFAVRRHLWGSHGNSTFPEFLHNMDYFKFHNMRPPFTYATLIRWAILEAPEKQRTLNEIYHWFTRMFAFFRNHPATWKNAIRHNLSLHKCFVRVESEKGAVWTVDELEFRKKR